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1

Glycine supplementation extends lifespan of male and female mice

Miller, Richard A., Harrison, David E., Astle, C. Michael, Bogue, Molly A., Brind, Joel, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin, Ladiges, Warren, Leeuwenburgh, Christiaan, Macchiarini, F

Journal:

Year:

2019

Language:

english

File:

PDF, 678 KB

english, 2019

2

Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues

Yousefzadeh, Matthew J., Wilkinson, John E., Hughes, Brian, Gadela, Namrata, Ladiges, Warren C., Vo, Nam, Niedernhofer, Laura J., Huffman, Derek M., Robbins, Paul D.

Journal:

Year:

2020

File:

PDF, 1.11 MB

2020

3

Mitochondrial point mutations do not limit the natural lifespan of mice

Vermulst, Marc, Bielas, Jason H, Kujoth, Gregory C, Ladiges, Warren C, Rabinovitch, Peter S, Prolla, Tomas A, Loeb, Lawrence A

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 169 KB

english, 2007

4

A Mitochondrial view of aging, reactive oxygen species and metastatic cancer

Warren Ladiges, Jonathan Wanagat, Bradley Preston, Lawrence Loeb, Peter Rabinovitch

Journal:

Year:

2010

Language:

english

File:

PDF, 145 KB

english, 2010

5

A New Preclinical Paradigm for Testing Anti-Aging Therapeutics

Ladiges, Warren, Snyder, Jessica M., Wilkinson, Erby, Imai, Denise M., Snider, Tim, Ge, Xuan, Ciol, Marcia, Pettan-Brewer, Christina, Pillai, Smitha P. S., Morton, John, Quarles, Ellen, Rabinovitch, P

Journal:

The Journals of Gerontology Series A Biological Sciences and Medical Sciences

Year:

2017

Language:

english

File:

PDF, 354 KB

english, 2017

6

Testing drug combinations to slow aging

Ladiges, Warren, Liggitt, Denny

Journal:

Pathobiology of Aging & Age-related Diseases

Year:

2018

Language:

english

File:

PDF, 700 KB

english, 2018

7

Cross species application of quantitative neuropathology assays developed for clinical Alzheimer’s disease samples

Urfer, Silvan R., Latimer, Caitlin S., Ladiges, Warren, Keene, C. Dirk, Benbow, Sarah, Harrison, Benjamin, Promislow, Daniel E.L., Kaeberlein, Matt, Kraemer, Brian C, Wang, Adrienne, Guscetti, Franco,

Journal:

Pathobiology of Aging & Age-related Diseases

Year:

2019

Language:

english

File:

PDF, 1.41 MB

english, 2019

8

Genetics of extreme human longevity to guide drug discovery for healthy ageing

Zhang, Zhengdong D., Milman, Sofiya, Lin, Jhih-Rong, Wierbowski, Shayne, Yu, Haiyuan, Barzilai, Nir, Gorbunova, Vera, Ladiges, Warren C., Niedernhofer, Laura J., Suh, Yousin, Robbins, Paul D., Vijg, J

Journal:

Nature Metabolism

Year:

2020

File:

PDF, 2.05 MB

2020

9

Treatment of feline leukemia and reversal of FeLV by ex vivo removal of IgG: A preliminary report

Frank R. Jones, Lois H. Yoshida, Warren C. Ladiges, Margaret A. Kenny

Journal:

Year:

1980

Language:

english

File:

PDF, 1.15 MB

english, 1980

10

Mitochondrial targeted catalase suppresses invasive breast cancer in mice

Jorming Goh, Linda Enns, Soroosh Fatemie, Heather Hopkins, John Morton, Christina Pettan-Brewer, Warren Ladiges

Journal:

Year:

2011

Language:

english

File:

PDF, 3.82 MB

english, 2011

11

The canine major histocompatibility complex. Supertypic specificities defined by the Primed Lymphocyte Test (PLT)

Warren C. Ladiges, Robert F. Raff, Steve Brown, H. Joachim Deeg, Rainer Storb

Journal:

Year:

1984

Language:

english

File:

PDF, 388 KB

english, 1984

12

Polymorphism of the sixth component of complement (C6) in the dog

Jeanne E. Anderson, Warren C. Ladiges, Eloise R. Giblett, Paul Weiden, Rainer Storb

Journal:

Biochemical Genetics

Year:

1983

Language:

english

File:

PDF, 257 KB

english, 1983

13

Polymorphism of the sixth component of complement (C6) in the dog

Jeanne E. Anderson, Warren C. Ladiges, Eloise R. Giblett, Paul Weiden, Rainer Storb

Journal:

Biochemical Genetics

Year:

1983

Language:

english

File:

PDF, 257 KB

english, 1983

14

FVB/N (H2q) mouse is resistant to arthritis induction and exhibits a genomic deletion of T-cell receptorVbeta gene segments

G. E. Osman, Mark C. Hannibal, Jon P. Anderson, Stephen R. Lasky, Warren C. Ladiges, Leroy Hood

Journal:

Year:

1999

Language:

english

File:

PDF, 135 KB

english, 1999

15

T-cell receptor Vbeta deletion and Valpha polymorphism are responsible for the resistance of SWR mouse to arthritis induction

G. E. Osman, Mark C. Hannibal, Jon P. Anderson, Saijai Cheunsuk, Stephen R. Lasky, H. Denny Liggitt, Warren C. Ladiges, Leroy E. Hood

Journal:

Year:

1999

Language:

english

File:

PDF, 180 KB

english, 1999

16

Lifespan extension in genetically modified mice

Warren Ladiges, Holly Van Remmen, Randy Strong, Yuji Ikeno, Piper Treuting, Peter Rabinovitch, Arlan Richardson

Journal:

Year:

2009

Language:

english

File:

PDF, 97 KB

english, 2009

17

Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice

Jesse C. Wiley, Christina Pettan-Brewer, Warren C. Ladiges

Journal:

Year:

2011

Language:

english

File:

PDF, 676 KB

english, 2011

18

Utility of a C57BL/6 ES line versus 129 ES lines for Targeted Mutations in Mice

Carol B. Ware, La' Akea N. Siverts, Angelique M. Nelson, John F. Morton, Warren C. Ladiges

Journal:

Transgenic Research

Year:

2003

Language:

english

File:

PDF, 75 KB

english, 2003

19

Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase

Kiranjit K. Dhillon, Julia M. Sidorova, Tina M. Albertson, Judith B. Anderson, Warren C. Ladiges, Peter S. Rabinovitch, Bradley D. Preston, Raymond J. Monnat Jr.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.30 MB

english, 2010

20

Hyperinsulinemia and insulin resistance in Wrn null mice fed a diabetogenic diet

Gina Moore, Susan Knoblaugh, Kathryn Gollahon, Peter Rabinovitch, Warren Ladiges

Journal:

Mechanisms of Ageing and Development

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

21

Approaches to determine clinical significance of genetic variants

Alasdair MacAuley, Warren C. Ladiges

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 145 KB

english, 2005

22

Comparative Mouse Genomics Centers Consortium: The Mouse Genotype Database

Jesse C. Wiley, Manjula Prattipati, Ching-Ping Lin, Warren Ladiges

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2006

Language:

english

File:

PDF, 446 KB

english, 2006

23

Tissue specific expression of PKR protein kinase in aging B6D2F1 mice

Warren Ladiges, John Morton, Collin Blakely, Michael Gale

Journal:

Mechanisms of Ageing and Development

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

24

Polymorphisms in the DNA repair gene XRCC1 and age-related disease

Warren Ladiges, Jesse Wiley, Alasdair MacAuley

Journal:

Mechanisms of Ageing and Development

Year:

2003

Language:

english

File:

PDF, 193 KB

english, 2003

25

Levels of dna damage are unaltered in mice overexpressing human catalase in nuclei

Samuel E Schriner, Charles E Ogburn, Annette C Smith, Terry G Newcomb, Warren C Ladiges, Martijn E.T Dollé, Jan Vijg, Ken-Ichiro Fukuchi, George M Martin

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 469 KB

english, 2000

26

Mice lacking the Cβ subunit of PKA are resistant to angiotensin II-induced cardiac hypertrophy and dysfunction

Linda C Enns, Kenneth L Bible, Mary J Emond, Warren C Ladiges

Journal:

BMC Research Notes

Year:

2010

Language:

english

File:

PDF, 950 KB

english, 2010

27

Protein kinase A signaling as an anti-aging target

Linda C. Enns, Warren Ladiges

Journal:

Ageing Research Reviews

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

28

Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

Hui-Young Lee, Cheol Soo Choi, Andreas L. Birkenfeld, Tiago C. Alves, Francois R. Jornayvaz, Michael J. Jurczak, Dongyan Zhang, Dong Kyun Woo, Gerald S. Shadel, Warren Ladiges, Peter S. Rabinovitch, J

Journal:

Cell Metabolism

Year:

2010

Language:

english

File:

PDF, 773 KB

english, 2010

29

Transgenic Mice Over-Expressing the C-99 Fragment of βPP with an α-Secretase Site Mutation Develop a Myopathy Similar to Human Inclusion Body Myositis

Lee-Way Jin, Mark G. Hearn, Charles E. Ogburn, Ngocthao Dang, David Nochlin, Warren C. Ladiges, George M. Martin

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.32 MB

english, 1998

30

Mitochondrial redox signaling and cancer invasiveness

Linda Enns, Warren Ladiges

Journal:

Journal of Bioenergetics and Biomembranes

Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012

31

Murine monoclonal antibodies cross-reactive with feline peripheral blood mononuclear cells

Grady H. Shelton, Warren C. Ladiges

Journal:

Veterinary Immunology and Immunopathology

Year:

1987

Language:

english

File:

PDF, 185 KB

english, 1987

32

A novel long term short interval physical activity regime improves body composition in mice

Jorming Goh, Warren C Ladiges

Journal:

BMC Research Notes

Year:

2013

Language:

english

File:

PDF, 270 KB

english, 2013

33

Decline in muscle strength and running endurance in klotho deficient C57BL/6 mice

Phelps, Michael, Pettan-Brewer, Christina, Ladiges, Warren, Yablonka-Reuveni, Zipora

Journal:

Year:

2013

Language:

english

File:

PDF, 396 KB

english, 2013

34

Rapid Detection of Bovine Type II Collagen-Specific T-Cell Hybridomas

VARMA, CHRIS K., LI, SARAH-WENQIN, HOOD, LEROY E., LADIGES, WARREN, OSMAN, GAMAL E.

Journal:

Year:

1997

Language:

english

File:

PDF, 8.47 MB

english, 1997

35

Monoclonal Antibodies to Canine Cell Surface Antigens: A Comparison of Screening Assays

LADIGES, WARREN C., DURKOPP, NATALIE, URBAN, CHRISTIAN, WULFF, JAN C., STORB, RAINER

Journal:

Year:

1984

Language:

english

File:

PDF, 422 KB

english, 1984

36

Expression of Human PKR Protein Kinase in Transgenic Mice

Ladiges, Warren, Morton, John, Hopkins, Heather, Wilson, Ruth, Filley, Gina, Ware, Carol, Gale, Michael

Journal:

Journal of Interferon & Cytokine Research

Year:

2002

Language:

english

File:

PDF, 454 KB

english, 2002

37

Chronic rapamycin treatment or lack of S6K1 does not reduce ribosome activity in vivo

Garelick, Michael G, MacKay, Vivian L, Yanagida, Aya, Academia, Emmeline C, Schreiber, Katherine H, Ladiges, Warren C, Kennedy, Brian K

Journal:

Year:

2013

Language:

english

File:

PDF, 1.79 MB

english, 2013

38

Deletion of P58IPK, the Cellular Inhibitor of the Protein Kinases PKR and PERK, Causes Bone Changes and Joint Degeneration in Mice

Gilbert, Sophie J., Meakin, Lee B., Bonnet, Cleo S., Nowell, Mari A., Ladiges, Warren C., Morton, John, Duance, Victor C., Mason, Deborah J.

Journal:

Frontiers in Endocrinology

Year:

2014

Language:

english

File:

PDF, 4.31 MB

english, 2014

39

The Geropathology Research Network: An Interdisciplinary Approach for Integrating Pathology Into Research on Aging

Ladiges, Warren, Ikeno, Yuji, Niedernhofer, Laura, McIndoe, Richard A., Ciol, Marcia A., Ritchey, Jerry, Liggitt, Denny

Journal:

The Journals of Gerontology Series A Biological Sciences and Medical Sciences

Year:

2015

Language:

english

File:

PDF, 835 KB

english, 2015

40

Application of the microfluidic-assisted replication track analysis to measure DNA repair in human and mouse cells

Welcsh, Piri, Kehrli, Keffy, Lazarchuk, Pavlo, Ladiges, Warren, Sidorova, Julia

Journal:

Year:

2016

Language:

english

File:

PDF, 2.78 MB

english, 2016

41

SELECTIVE INHIBITION OF THE CANINE MIXED LYMPHOCYTE RESPONSE BY HLA-DR AND DP-REACTIVE MONOCLONAL ANTIBODIES

Ladiges, Warren C., Pesando, John M., Severns, Eileen, Longton, Gary, Deeg, H. Joachim, Storb, Rainer

Journal:

Transplantation Journal

Year:

1988

File:

PDF, 492 KB

1988

42

RECOGNITION OF TARGET CELL DETERMINANTS ASSOCIATED WITH DLA-D-LOCUS-ENCODED ANTIGENS BY CANINE CYTOTOXIC LYMPHOCYTES

RAFF, ROBERT F., STORB, RAINER, LADIGES, WARREN C., DEEG, H. JOACHIM

Journal:

Transplantation Journal

Year:

1985

File:

PDF, 560 KB

1985

43

Novel application of a Radial Water Tread maze can distinguish cognitive deficits in mice with traumatic brain injury

Cline, Marcella M., Yumul, Josh C., Hysa, Lisa, Murra, Dalia, Garwin, Gregory G., Cook, David G., Ladiges, Warren C., Minoshima, Satoshi, Cross, Donna J.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

44

Self-motivated and stress-response performance assays in mice are age-dependent

Ge, Xuan, Ciol, Marcia A., Pettan-Brewer, Christina, Goh, Jorming, Rabinovitch, Peter, Ladiges, Warren

Journal:

Experimental Gerontology

Year:

2017

Language:

english

File:

PDF, 469 KB

english, 2017

45

Curcumin suppresses intestinal polyps in APC Min mice fed a high fat diet

Pettan-Brewer, Christina, Morton, John, Mangalindan, Ruby, Ladiges, Warren

Journal:

Pathobiology of Aging & Age-related Diseases

Year:

2011

Language:

english

File:

PDF, 471 KB

english, 2011

46

Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines

Keene, C. Dirk, Darvas, Martin, Kraemer, Brian, Liggitt, Denny, Sigurdson, Christina, Ladiges, Warren

Journal:

Pathobiology of Aging & Age-related Diseases

Year:

2016

Language:

english

File:

PDF, 599 KB

english, 2016

47

Chronic low-level exposure to the common seafood toxin domoic acid causes cognitive deficits in mice

Lefebvre, Kathi A., Kendrick, Preston S., Ladiges, Warren, Hiolski, Emma M., Ferriss, Bridget E., Smith, Donald R., Marcinek, David J.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

48

Mitochondrial Targeted Catalase Protects Against High-Fat Diet-Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation

Lee, Hui-Young, Lee, Jae Sung, Alves, Tiago, Ladiges, Warren, Rabinovitch, Peter S., Jurczak, Michael J., Choi, Cheol Soo, Shulman, Gerald I., Samuel, Varman T.

Journal:

Year:

2017

Language:

english

File:

PDF, 629 KB

english, 2017

49

The quality control theory of aging

Ladiges, Warren

Journal:

Pathobiology of Aging & Age-related Diseases

Year:

2014

Language:

english

File:

PDF, 550 KB

english, 2014

50

Animal models play a vital role in translational aging research

Ladiges, Warren C.

Journal:

Pathobiology of Aging & Age-related Diseases

Year:

2015

Language:

english

File:

PDF, 553 KB

english, 2015